Biostimulator treatments, which fall under the category of Regenerative Aesthetics, have become a top choice for individuals seeking non-invasive, lasting, long-term volume enhancement and natural-looking skin rejuvenation with no downtime.
What Are Biostimulators?
Biostimulators are injectable treatments that go beyond the short-term plumping effects of traditional dermal fillers. They stimulate your body’s natural production of collagen and/or elastin to improve skin firmness, elasticity, and texture with natural-looking, long-lasting results.
How Are Biostimulators Different from Traditional Dermal Fillers?
Biostimulators like Sculptra and Radiesse differ from traditional hyaluronic acid (HA) dermal fillers like Juvéderm or Restylane in how they work, where they work, how long they last, and the results they can deliver. In general:
- Dermal Fillers provide instant yet temporary hydration and volume. They’re typically best for clients in their 20s with minimal or early onset signs of aging and/or those seeking immediate enhancements. Ideal for fine lines, lips, and under the eyes.
- Biostimulators provide gradual, lasting, longer-term volume and skin rejuvenation that builds over time. They’re typically best for clients in their 30s to 60s with moderate to advanced signs of aging in the face, neck, chest, and hands.
Top Biostimulator Benefits:
Long-Lasting Results
Last up to 4x longer than HA dermal fillers, depending on product type and treatment area.
Natural Volume Enhancement
Stimulate collagen and/or elastin production for a refreshed, not “filled”, appearance over time.
Improved Skin Quality
Lasting, long-term rejuvenating effects that improve skin tone, texture, and elasticity.
Radiesse vs Sculptra: What’s the Difference?
When it comes to long-lasting, biostimulatory injectables, Sculptra and Radiesse are two of the most effective options available today, and both help to restore structure, firmness, and youthful volume over time. While they share this biostimulatory action, they differ in how they behave in the skin, how quickly results appear, and the types of concerns they treat best. Understanding the unique properties of each can help determine the best approach for your skin goals.
Radiesse: Biostimulator + Dermal Filler Hybrid
Radiesse is made from calcium hydroxylapatite (CaHA). It’s dual action approach delivers instant volume, lift, contouring, and gradual stimulation of five types of collagen and elastin over time. Ideal for individuals with more advanced signs of aging who want immediate AND lasting, long-term skin rejuvenation.
Radiesse typically requires 1-2 treatments spaced 4-6 weeks apart, with no downtime or aftercare required. Results last for ~18-24+ months.
Radiesse Is Especially Effective For:
- Jawline, chin, and cheek sculpting and definition
- Deep wrinkles and lines in the mid-lower face
- Volume loss in the hands
- Skin quality improvements in the face, neck, chest, arms, and more (when hyperdiluted)
- Treating areas where Sculptra isn’t suitable
Sculptra: Biostimulator Only
Sculptra is made from poly-L-lactic acid (PLLA). It works by stimulating the production of two types of collagen to rejuvenate skin over time without adding immediate volume. Ideal for individuals with moderate signs of aging who want subtle, highly natural-looking results.
Sculptra typically requires 2-3 treatments spaced 4-8 weeks apart, with no downtime and minimal aftercare required. Results last for ~2+ years.
Sculptra Is Especially Effective For:
- Diffuse, full-face volume correction
- Skin quality rejuvenation
- Correcting facial hollows (cheeks, temples)
- Buttocks enhancement
- Treating areas where Radiesse isn’t suitable
Is Radiesse or Sculptra Better?
A common question we get at Juvea Aesthetics is: “Which biostimulator is right for me?” The answer? “It depends…”.
Both Sculptra and Radiesse offer powerful rejuvenation and, in some cases, they can even be used together. Your best option depends on your skin condition, goals, treatment areas, and desired timeline.
Radiesse May be Best if:
You’re looking for instant volume, lift, contouring and progressive long-term structural support and lasting skin rejuvenation in the mid-lower face, neck, décolletage, or hands.
Sculptra May be Best if:
You’re looking for the most natural looking results and gradual, lasting full face volume correction — especially in the cheeks and temples, and/or buttock enhancement.
Can Biostimulators Be Combined with Other Treatments?
Biostimulators can be layered with other aesthetic treatments for optimal results. However, you can trust that Juvea Aesthetics will never recommend any treatments that are unnecessary or unsuitable for you. Common treatment combinations often include:
Why Choose Juvea Aesthetics in Calgary?
At Juvea Aesthetics in Calgary, we work with you to create a customized treatment plan based on your skin condition, concerns, and ideal short and long-term objectives.
- Highly qualified team of expert injectors and aestheticians
- Specialize in natural-looking enhancement results
- Expertise with diverse skin types and facial anatomies
- 2025 list of Top Medispas in Calgary
- Trusted and recommended by hundreds of clients
Frequently Asked Questions (FAQs)
Yes! Both Radiesse and Sculptra are Health Canada and FDA-approved.
No. As non-hyaluronic acid (HA) fillers, they cannot be dissolved with hyaluronidase.
Discover your most confident self with Juvea Aesthetics in Calgary, Canada. Juvea is a premier medical aesthetics clinic dedicated to helping clients look and feel their best through science-backed, personalized, temporary and long-term skin improvement, healing and rejuvenation solutions. Our expert team combines certified ability with innovation to deliver natural, lasting, stunning results.